The phrase "most hunky dory" refers to something that is going well, smoothly or successfully. However, antonyms for this phrase could include words like problematic, troublesome, difficult, rough or challenging. A situation or experience that may be categorized as "most hunky dory" might be described as the complete opposite if it is fraught with difficulties or issues that need to be resolved. It's important to remember that life is full of ups and downs, and while things may be going well today it's always good to be prepared for any challenges that may arise in the future.