Hepatosplenic T-cell lymphoma (HSTCL) is a rare type of non-Hodgkin's lymphoma that affects the liver, spleen, and bone marrow. Some synonyms for HSTCL include peripheral T-cell lymphoma not otherwise specified, hepatosplenic gamma-delta T-cell lymphoma, and T-cell lymphoma with isochromosome 7q. These alternate names for HSTCL help to describe the specific subtype of T-cell lymphoma that affects these particular organs and tissues. Due to its rarity, HSTCL can be difficult to diagnose and treat. If you or a loved one has been diagnosed with HSTCL, seek out a healthcare professional who has experience in treating this particular type of lymphoma.